Metanalysis of Vaccine Efficacy for Monkeypox According to Clinical Criteria of History Taking, Clinical Features and Laboratory Investigation

Monkeypox virus is DNA of Orthopoxvirus. The zoonosis disease first diagnosed in the Democratic Republic Congo 1970 and originally transmitted from Vertebrate Reservoir. In 1796, Edward Jenner was physician achieved vaccine prove its efficacy through exposing James Phipps to smallpox after immunization. current study revises mortality rate monkeypox. It mainly Squirrels human cause ranging 2.7 10.1%. Globally, it estimated 4.4% cases. Based on review study, effectiveness preventing monkeypox quite variable due several selective clinical cases criteria such as history taking features laboratory investigation, which modify statistical result efficacy. clarifies faults calculation by eliminating reasons estimating household find be 16.3% whereas total Vaccine 0.6%. Using preventive measures are line avoid infection therefore healthcare workers must adhere control precautions. A warns scientists create rather than depending lacking evidence treatment.